Partitioning and diffusion of proteins and linear polymers in polyacrylamide gels

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Partitioning and diffusion of proteins and linear polymers in polyacrylamide gels.

The equilibrium partition coefficient (K) and diffusion coefficient (Dgel) of two proteins and two linear polymers were measured as a function of polymer content of a 2.7% cross-linked polyacrylamide (PA) gel. The gel concentration, expressed as a volume percentage of PA in the gel (phi), varied between 0 and 14%. The measurements were made by fluorescence spectroscopy; fluorescent dyes were co...

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Visible fluorescent detection of proteins in polyacrylamide gels without staining.

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ژورنال

عنوان ژورنال: Biophysical Journal

سال: 1996

ISSN: 0006-3495

DOI: 10.1016/s0006-3495(96)79712-6